Maternal and Zygotic aldh1a2 Activity Is Required for Pancreas Development in Zebrafish

We have isolated and characterized a novel zebrafish pancreas mutant. Mutant embryos lack expression of isl1 and sst in the endocrine pancreas, but retain isl1 expression in the CNS. Non-endocrine endodermal gene expression is less affected in the mutant, with varying degrees of residual expression...

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Detalles Bibliográficos
Autores principales: Alexa, Kristen, Choe, Seong-Kyu, Hirsch, Nicolas, Etheridge, Letitiah, Laver, Elizabeth, Sagerström, Charles G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788244/
https://www.ncbi.nlm.nih.gov/pubmed/20011517
http://dx.doi.org/10.1371/journal.pone.0008261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788244/
https://www.ncbi.nlm.nih.gov/pubmed/20011517
http://dx.doi.org/10.1371/journal.pone.0008261

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