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Maternal and Zygotic aldh1a2 Activity Is Required for Pancreas Development in Zebrafish
We have isolated and characterized a novel zebrafish pancreas mutant. Mutant embryos lack expression of isl1 and sst in the endocrine pancreas, but retain isl1 expression in the CNS. Non-endocrine endodermal gene expression is less affected in the mutant, with varying degrees of residual expression...
Autores principales: | Alexa, Kristen, Choe, Seong-Kyu, Hirsch, Nicolas, Etheridge, Letitiah, Laver, Elizabeth, Sagerström, Charles G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788244/ https://www.ncbi.nlm.nih.gov/pubmed/20011517 http://dx.doi.org/10.1371/journal.pone.0008261 |
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