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Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways
BACKGROUND: Osteosarcoma is the most prevalent primary malignant bone tumour in children and young adults, with poor survival in 40% of patients. To identify the signalling pathways involved in tumourigenesis, we compared gene expression in osteosarcoma with that in its presumed normal counterparts....
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788255/ https://www.ncbi.nlm.nih.gov/pubmed/19888226 http://dx.doi.org/10.1038/sj.bjc.6605405 |