Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways

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BACKGROUND: Osteosarcoma is the most prevalent primary malignant bone tumour in children and young adults, with poor survival in 40% of patients. To identify the signalling pathways involved in tumourigenesis, we compared gene expression in osteosarcoma with that in its presumed normal counterparts....

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Detalles Bibliográficos
Autores principales: Cleton-Jansen, A-M, Anninga, J K, Briaire-de Bruijn, I H, Romeo, S, Oosting, J, Egeler, R M, Gelderblom, H, Taminiau, A H M, Hogendoorn, P C W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788255/
https://www.ncbi.nlm.nih.gov/pubmed/19888226
http://dx.doi.org/10.1038/sj.bjc.6605405

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