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The state of the art: immune-mediated mechanisms of monoclonal antibodies in cancer therapy

A number of antibody products have now become accepted as effective anti-cancer therapies. Despite being mainly designed to act by inhibiting functional tumour antigens, there is increasing evidence that Fc-mediated engagement of the immune system is an important contributor to the efficacy of sever...

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Detalles Bibliográficos
Autores principales: Griggs, J, Zinkewich-Peotti, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788263/
https://www.ncbi.nlm.nih.gov/pubmed/19809433
http://dx.doi.org/10.1038/sj.bjc.6605349