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Prediction of avian influenza A binding preference to human receptor using conformational analysis of receptor bound to hemagglutinin
BACKGROUND: It is known that the highly pathogenic avian influenza A virus H5N1 binds strongly and with high specificity to the avian-type receptor by its hemagglutinin surface protein. This specificity is normally a barrier to viral transmission from birds to humans. However, strains may emerge wit...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788377/ https://www.ncbi.nlm.nih.gov/pubmed/19958488 http://dx.doi.org/10.1186/1471-2164-10-S3-S24 |