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Prediction of avian influenza A binding preference to human receptor using conformational analysis of receptor bound to hemagglutinin

BACKGROUND: It is known that the highly pathogenic avian influenza A virus H5N1 binds strongly and with high specificity to the avian-type receptor by its hemagglutinin surface protein. This specificity is normally a barrier to viral transmission from birds to humans. However, strains may emerge wit...

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Detalles Bibliográficos
Autores principales: Jongkon, Nipa, Mokmak, Wanwimon, Chuakheaw, Daungmanee, Shaw, Philip J, Tongsima, Sissades, Sangma, Chak
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788377/
https://www.ncbi.nlm.nih.gov/pubmed/19958488
http://dx.doi.org/10.1186/1471-2164-10-S3-S24