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Human liver rate-limiting enzymes influence metabolic flux via branch points and inhibitors

BACKGROUND: Rate-limiting enzymes, because of their relatively low velocity, are believed to influence metabolic flux in pathways. To investigate their regulatory role in metabolic networks, we look at the global organization and interactions between rate-limiting enzymes and compounds such as branc...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Qu, Hong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788385/
https://www.ncbi.nlm.nih.gov/pubmed/19958496
http://dx.doi.org/10.1186/1471-2164-10-S3-S31