Sox2 Is Required for Maintenance and Differentiation of Bronchiolar Clara, Ciliated, and Goblet Cells

The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis. In the present work, we demonstrate that expression of So...

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Detalles Bibliográficos
Autores principales: Tompkins, David H., Besnard, Valérie, Lange, Alexander W., Wert, Susan E., Keiser, Angela R., Smith, April N., Lang, Richard, Whitsett, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788414/
https://www.ncbi.nlm.nih.gov/pubmed/20011520
http://dx.doi.org/10.1371/journal.pone.0008248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788414/
https://www.ncbi.nlm.nih.gov/pubmed/20011520
http://dx.doi.org/10.1371/journal.pone.0008248

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