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Patterned Neuroprotection in the Inpp4a(wbl) Mutant Mouse Cerebellum Correlates with the Expression of Eaat4
The weeble mutant mouse has a frame shift mutation in inositol polyphosphate 4-phosphatase type I (Inpp4a). The phenotype is characterized by an early onset cerebellar ataxia and neurodegeneration, especially apparent in the Purkinje cells. Purkinje cell loss is a common pathological finding in many...
Autores principales: | Sachs, Andrew J., David, Samuel A., Haider, Neena B., Nystuen, Arne M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788419/ https://www.ncbi.nlm.nih.gov/pubmed/20011524 http://dx.doi.org/10.1371/journal.pone.0008270 |
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