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N-Cadherin Negatively Regulates Osteoblast Proliferation and Survival by Antagonizing Wnt, ERK and PI3K/Akt Signalling

BACKGROUND: Osteoblasts are bone forming cells that play an essential role in osteogenesis. The elucidation of the mechanisms that control osteoblast number is of major interest for the treatment of skeletal disorders characterized by abnormal bone formation. Canonical Wnt signalling plays an import...

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Detalles Bibliográficos
Autores principales: Haÿ, Eric, Nouraud, Alexandra, Marie, Pierre J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788421/
https://www.ncbi.nlm.nih.gov/pubmed/20011526
http://dx.doi.org/10.1371/journal.pone.0008284