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Association between the methylenetetrahydrofolate reductase C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate. The non-synonymous single nucleotide polymorphism (nsSNP), C677T (Ala>Val, rs1801133), has been verified to impair enzyme activity. The association with cancer susceptibility, including hepatocell...

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Detalles Bibliográficos
Autores principales: Jin, Fei, Qu, Li-Shuai, Shen, Xi-Zhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788519/
https://www.ncbi.nlm.nih.gov/pubmed/19930673
http://dx.doi.org/10.1186/1746-1596-4-39