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Role of lysophosphatidic acid receptor LPA(2 )in the development of allergic airway inflammation in a murine model of asthma
BACKGROUND: Lysophosphatidic acid (LPA) plays a critical role in airway inflammation through G protein-coupled LPA receptors (LPA(1-3)). We have demonstrated that LPA induced cytokine and lipid mediator release in human bronchial epithelial cells. Here we provide evidence for the role of LPA and LPA...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788521/ https://www.ncbi.nlm.nih.gov/pubmed/19930563 http://dx.doi.org/10.1186/1465-9921-10-114 |