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Role of lysophosphatidic acid receptor LPA(2 )in the development of allergic airway inflammation in a murine model of asthma

BACKGROUND: Lysophosphatidic acid (LPA) plays a critical role in airway inflammation through G protein-coupled LPA receptors (LPA(1-3)). We have demonstrated that LPA induced cytokine and lipid mediator release in human bronchial epithelial cells. Here we provide evidence for the role of LPA and LPA...

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Detalles Bibliográficos
Autores principales: Zhao, Yutong, Tong, Jiankun, He, Donghong, Pendyala, Srikanth, Evgeny, Berdyshev, Chun, Jerold, Sperling, Anne I, Natarajan, Viswanathan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788521/
https://www.ncbi.nlm.nih.gov/pubmed/19930563
http://dx.doi.org/10.1186/1465-9921-10-114