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Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration

ERK signaling regulates focal adhesion disassembly during cell movement, and increased ERK signaling frequently contributes to enhanced motility of human tumor cells. We previously found that the ERK scaffold MEK Partner 1 (MP1) is required for focal adhesion disassembly in fibroblasts. Here we test...

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Detalles Bibliográficos
Autores principales: Park, Electa R, Pullikuth, Ashok K, Bailey, Evangeline M, Mercante, Donald E, Catling, Andrew D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788567/
https://www.ncbi.nlm.nih.gov/pubmed/19930650
http://dx.doi.org/10.1186/1478-811X-7-26