Use of nfsB, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in Neisseria gonorrhoeae

BACKGROUND: Organisms that are sensitive to nitrofurantoin express a nitroreductase. Since bacterial resistance to this compound results primarily from mutations in the gene encoding nitroreductase, the resulting loss of function of nitroreductase results in a selectable phenotype; resistance to nit...

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Detalles Bibliográficos
Autores principales: Stein, Daniel C, Carrizosa, Esteban, Dunham, Stephen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788575/
https://www.ncbi.nlm.nih.gov/pubmed/19930647
http://dx.doi.org/10.1186/1471-2180-9-239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788575/
https://www.ncbi.nlm.nih.gov/pubmed/19930647
http://dx.doi.org/10.1186/1471-2180-9-239

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