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A Matrix Metalloproteinase-1/Protease Activated Receptor-1 signaling axis promotes melanoma invasion and metastasis

Hallmarks of malignant melanoma are its propensity to metastasize and its resistance to treatment, giving patients with advanced disease a poor prognosis. The transition of melanoma from non-invasive radial growth phase (RGP) to invasive and metastatically competent vertical growth phase (VGP) is a...

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Detalles Bibliográficos
Autores principales: Blackburn, Jessica S., Liu, Ingrid, Coon, Charles I., Brinckerhoff, Constance E.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788659/
https://www.ncbi.nlm.nih.gov/pubmed/19734937
http://dx.doi.org/10.1038/onc.2009.272