PIM1 Phosphorylates and Negatively Regulates ASK1-mediated Apoptosis

The serine/threonine kinase, PIM1, is involved in promoting cell survival in part by phosphorylation and inhibition of proapoptotic proteins. ASK1, a mitogen-activated protein kinase kinase kinase (MAPKKK), is involved in the so-called stress-activated pathways that contribute to apoptotic cell deat...

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Detalles Bibliográficos
Autores principales: Gu, Juan Jenny, Wang, Zeping, Reeves, Raymond, Magnuson, Nancy S.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788665/
https://www.ncbi.nlm.nih.gov/pubmed/19749799
http://dx.doi.org/10.1038/onc.2009.276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788665/
https://www.ncbi.nlm.nih.gov/pubmed/19749799
http://dx.doi.org/10.1038/onc.2009.276

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