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PIM1 Phosphorylates and Negatively Regulates ASK1-mediated Apoptosis
The serine/threonine kinase, PIM1, is involved in promoting cell survival in part by phosphorylation and inhibition of proapoptotic proteins. ASK1, a mitogen-activated protein kinase kinase kinase (MAPKKK), is involved in the so-called stress-activated pathways that contribute to apoptotic cell deat...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788665/ https://www.ncbi.nlm.nih.gov/pubmed/19749799 http://dx.doi.org/10.1038/onc.2009.276 |