Cargando…

The Catalytic Subunit of Protein Phosphatase 1 Gamma Regulates Thrombin-Induced Murine Platelet α(IIb)β(3) Function

BACKGROUND: Hemostasis and thrombosis are regulated by agonist-induced activation of platelet integrin α(IIb)β(3). Integrin activation, in turn is mediated by cellular signaling via protein kinases and protein phosphatases. Although the catalytic subunit of protein phosphatase 1 (PP1c) interacts wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Gushiken, Francisca C., Hyojeong, Han, Pradhan, Subhashree, Langlois, Kimberly W., Alrehani, Nawaf, Cruz, Miguel A., Rumbaut, Rolando E., Vijayan, K. Vinod
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788699/
https://www.ncbi.nlm.nih.gov/pubmed/20016849
http://dx.doi.org/10.1371/journal.pone.0008304