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The Catalytic Subunit of Protein Phosphatase 1 Gamma Regulates Thrombin-Induced Murine Platelet α(IIb)β(3) Function
BACKGROUND: Hemostasis and thrombosis are regulated by agonist-induced activation of platelet integrin α(IIb)β(3). Integrin activation, in turn is mediated by cellular signaling via protein kinases and protein phosphatases. Although the catalytic subunit of protein phosphatase 1 (PP1c) interacts wit...
Autores principales: | Gushiken, Francisca C., Hyojeong, Han, Pradhan, Subhashree, Langlois, Kimberly W., Alrehani, Nawaf, Cruz, Miguel A., Rumbaut, Rolando E., Vijayan, K. Vinod |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788699/ https://www.ncbi.nlm.nih.gov/pubmed/20016849 http://dx.doi.org/10.1371/journal.pone.0008304 |
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