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The conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase

BACKGROUND: The shikimate pathway is an attractive target for the development of antitubercular agents because it is essential in Mycobacterium tuberculosis, the causative agent of tuberculosis, but absent in humans. M. tuberculosis aroE-encoded shikimate dehydrogenase catalyzes the forth reaction i...

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Detalles Bibliográficos
Autores principales: Rodrigues, Valnês S, Breda, Ardala, Santos, Diógenes S, Basso, Luiz A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789096/
https://www.ncbi.nlm.nih.gov/pubmed/19917104
http://dx.doi.org/10.1186/1756-0500-2-227