Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

The presence of Aβ(pE3) (N-terminal truncated Aβ starting with pyroglutamate) in Alzheimer’s disease (AD) has received considerable attention since the discovery that this peptide represents a dominant fraction of Aβ peptides in senile plaques of AD brains. This was later confirmed by other reports...

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Detalles Bibliográficos
Autores principales: Wirths, Oliver, Bethge, Tobias, Marcello, Andrea, Harmeier, Anja, Jawhar, Sadim, Lucassen, Paul J., Multhaup, Gerd, Brody, David L., Esparza, Thomas, Ingelsson, Martin, Kalimo, Hannu, Lannfelt, Lars, Bayer, Thomas A.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2009
Materias:
Dementias - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789212/
https://www.ncbi.nlm.nih.gov/pubmed/19823761
http://dx.doi.org/10.1007/s00702-009-0314-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789212/
https://www.ncbi.nlm.nih.gov/pubmed/19823761
http://dx.doi.org/10.1007/s00702-009-0314-x

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