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MAP kinase dependent cyclinE/cdk2 activity promotes DNA replication in early sea urchin embryos

Sea urchins provide an excellent model for studying cell cycle control mechanisms governing DNA replication in vivo. Fertilization and cell cycle progression are tightly coordinated by Ca(2+) signals, but the mechanisms underlying the onset of DNA replication after fertilization remain less clear. I...

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Detalles Bibliográficos
Autores principales: Kisielewska, J., Philipova, R., Huang, J.-Y., Whitaker, M.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789238/
https://www.ncbi.nlm.nih.gov/pubmed/19665013
http://dx.doi.org/10.1016/j.ydbio.2009.07.043