Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects

The enzyme myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyses the co-translational covalent attachment of the fatty acid myristate to the N-terminus of target proteins. NMT is known to be essential for viability in Trypanosoma brucei and Leishmania major. Here we describe phenotypic analys...

Descripción completa

Detalles Bibliográficos
Autores principales: Price, Helen P., Güther, M. Lucia S., Ferguson, Michael A.J., Smith, Deborah F.
Formato: Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789243/
https://www.ncbi.nlm.nih.gov/pubmed/19782106
http://dx.doi.org/10.1016/j.molbiopara.2009.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789243/
https://www.ncbi.nlm.nih.gov/pubmed/19782106
http://dx.doi.org/10.1016/j.molbiopara.2009.09.006

Ejemplares similares