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Bistability of Mitochondrial Respiration Underlies Paradoxical Reactive Oxygen Species Generation Induced by Anoxia

Increased production of reactive oxygen species (ROS) in mitochondria underlies major systemic diseases, and this clinical problem stimulates a great scientific interest in the mechanism of ROS generation. However, the mechanism of hypoxia-induced change in ROS production is not fully understood. To...

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Detalles Bibliográficos
Autores principales: Selivanov, Vitaly A., Votyakova, Tatyana V., Zeak, Jennifer A., Trucco, Massimo, Roca, Josep, Cascante, Marta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789320/
https://www.ncbi.nlm.nih.gov/pubmed/20041200
http://dx.doi.org/10.1371/journal.pcbi.1000619