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Bistability of Mitochondrial Respiration Underlies Paradoxical Reactive Oxygen Species Generation Induced by Anoxia
Increased production of reactive oxygen species (ROS) in mitochondria underlies major systemic diseases, and this clinical problem stimulates a great scientific interest in the mechanism of ROS generation. However, the mechanism of hypoxia-induced change in ROS production is not fully understood. To...
Autores principales: | Selivanov, Vitaly A., Votyakova, Tatyana V., Zeak, Jennifer A., Trucco, Massimo, Roca, Josep, Cascante, Marta |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789320/ https://www.ncbi.nlm.nih.gov/pubmed/20041200 http://dx.doi.org/10.1371/journal.pcbi.1000619 |
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