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Erk1 and Erk2 Regulate Endothelial Cell Proliferation and Migration during Mouse Embryonic Angiogenesis

Angiogenesis is a complex process orchestrated by both growth factors and cell adhesion and is initiated by focal degradation of the vascular basement membrane with subsequent migration and proliferation of endothelial cells. The Ras/Raf/MEK/ERK pathway is required for EC function during angiogenesi...

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Detalles Bibliográficos
Autores principales: Srinivasan, Ruchika, Zabuawala, Tahera, Huang, Hong, Zhang, Jianying, Gulati, Parul, Fernandez, Soledad, Karlo, J. Colleen, Landreth, Gary E., Leone, Gustavo, Ostrowski, Michael C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789384/
https://www.ncbi.nlm.nih.gov/pubmed/20011539
http://dx.doi.org/10.1371/journal.pone.0008283