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CTL mobilization to virus-infected tissue requires CD4(+) T cell help

CD4(+) T helper cells are well known for their role in providing critical signals during priming of cytotoxic CD8(+) T lymphocyte (CTL) responses in vivo. T help is required for the generation of primary CTL responses as well as in promoting protective CD8(+) memory T cell development1. However, the...

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Detalles Bibliográficos
Autores principales: Nakanishi, Yusuke, Lu, Bao, Gerard, Craig, Iwasaki, Akiko
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789415/
https://www.ncbi.nlm.nih.gov/pubmed/19898495
http://dx.doi.org/10.1038/nature08511