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Characterisation of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats

BACKGROUND: Continuous exposure to tobacco smoke (TS) is a key cause of chronic obstructive pulmonary disease (COPD), a complex multifactorial disease that is difficult to model in rodents. The spontaneously hypertensive (SH) rat exhibits several COPD-associated co-morbidities such as hypertension a...

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Detalles Bibliográficos
Autores principales: Bolton, Sarah J, Pinnion, Kate, Oreffo, Victor, Foster, Martyn, Pinkerton, Kent E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789729/
https://www.ncbi.nlm.nih.gov/pubmed/19930705
http://dx.doi.org/10.1186/1465-9921-10-118