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Characterisation of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats
BACKGROUND: Continuous exposure to tobacco smoke (TS) is a key cause of chronic obstructive pulmonary disease (COPD), a complex multifactorial disease that is difficult to model in rodents. The spontaneously hypertensive (SH) rat exhibits several COPD-associated co-morbidities such as hypertension a...
Autores principales: | Bolton, Sarah J, Pinnion, Kate, Oreffo, Victor, Foster, Martyn, Pinkerton, Kent E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789729/ https://www.ncbi.nlm.nih.gov/pubmed/19930705 http://dx.doi.org/10.1186/1465-9921-10-118 |
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