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A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells

BACKGROUND: The deposition of unconjugated bilirubin (UCB) in selected regions of the brain results in irreversible neuronal damage, or Bilirubin Encephalopathy (BE). Although UCB impairs a large number of cellular functions in other tissues, the basic mechanisms of neurotoxicity have not yet been f...

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Detalles Bibliográficos
Autores principales: Calligaris, Raffaella, Bellarosa, Cristina, Foti, Rossana, Roncaglia, Paola, Giraudi, Pablo, Krmac, Helena, Tiribelli, Claudio, Gustincich, Stefano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789749/
https://www.ncbi.nlm.nih.gov/pubmed/19925663
http://dx.doi.org/10.1186/1471-2164-10-543