The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases

Prion diseases reflect conformational conversion of benign isoforms of prion protein (PrP(C)) to malignant PrP(Sc) isoforms. Networks perturbed by PrP(Sc) accumulation and their ties to pathological events are poorly understood. Time-course transcriptomic and phenotypic data in animal models are cri...

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Detalles Bibliográficos
Autores principales: Gehlenborg, Nils, Hwang, Daehee, Lee, Inyoul Y., Yoo, Hyuntae, Baxter, David, Petritis, Brianne, Pitstick, Rose, Marzolf, Bruz, DeArmond, Stephen J., Carlson, George A., Hood, Leroy
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790306/
https://www.ncbi.nlm.nih.gov/pubmed/20157484
http://dx.doi.org/10.1093/database/bap011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790306/
https://www.ncbi.nlm.nih.gov/pubmed/20157484
http://dx.doi.org/10.1093/database/bap011

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