Cargando…
The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases
Prion diseases reflect conformational conversion of benign isoforms of prion protein (PrP(C)) to malignant PrP(Sc) isoforms. Networks perturbed by PrP(Sc) accumulation and their ties to pathological events are poorly understood. Time-course transcriptomic and phenotypic data in animal models are cri...
Autores principales: | Gehlenborg, Nils, Hwang, Daehee, Lee, Inyoul Y., Yoo, Hyuntae, Baxter, David, Petritis, Brianne, Pitstick, Rose, Marzolf, Bruz, DeArmond, Stephen J., Carlson, George A., Hood, Leroy |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790306/ https://www.ncbi.nlm.nih.gov/pubmed/20157484 http://dx.doi.org/10.1093/database/bap011 |
Ejemplares similares
-
A systems approach to prion disease
por: Hwang, Daehee, et al.
Publicado: (2009) -
Core transcriptional regulatory circuits in prion diseases
por: Kim, Taek-Kyun, et al.
Publicado: (2020) -
Levels of the Mahogunin Ring Finger 1 E3 Ubiquitin Ligase Do Not Influence Prion Disease
por: Silvius, Derek, et al.
Publicado: (2013) -
Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrP(Sc) Accumulation
por: Westaway, David, et al.
Publicado: (2011) -
PrP(Sc )accumulation in neuronal plasma membranes links Notch-1 activation to dendritic degeneration in prion diseases
por: DeArmond, Stephen J, et al.
Publicado: (2010)