Mitochondrial Mislocalization Underlies Aβ42-Induced Neuronal Dysfunction in a Drosophila Model of Alzheimer's Disease

The amyloid-β 42 (Aβ42) is thought to play a central role in the pathogenesis of Alzheimer's disease (AD). However, the molecular mechanisms by which Aβ42 induces neuronal dysfunction and degeneration remain elusive. Mitochondrial dysfunctions are implicated in AD brains. Whether mitochondrial...

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Detalles Bibliográficos
Autores principales: Iijima-Ando, Kanae, Hearn, Stephen A., Shenton, Christopher, Gatt, Anthony, Zhao, LiJuan, Iijima, Koichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790372/
https://www.ncbi.nlm.nih.gov/pubmed/20016833
http://dx.doi.org/10.1371/journal.pone.0008310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790372/
https://www.ncbi.nlm.nih.gov/pubmed/20016833
http://dx.doi.org/10.1371/journal.pone.0008310

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