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Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats
Brain function declines with age and is associated with diminishing mitochondrial integrity. The neuronal mitochondrial ultrastructural changes of young (4 months) and old (21 months) F344 rats supplemented with two mitochondrial metabolites, acetyl-L-carnitine (ALCAR, 0.2%[wt/vol] in the drinking w...
Autores principales: | Aliev, Gjumrakch, Liu, Jiankang, Shenk, Justin C, Fischbach, Kathryn, Pacheco, Gerardo J, Chen, Shu G, Obrenovich, Mark E, Ward, Walter F, Richardson, Arlan G, Smith, Mark A, Gasimov, Eldar, Perry, George, Ames, Bruce N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790425/ https://www.ncbi.nlm.nih.gov/pubmed/18373733 http://dx.doi.org/10.1111/j.1582-4934.2008.00324.x |
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