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Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae)

BACKGROUND: ADARs are RNA editing enzymes that target double stranded RNA and convert adenosine to inosine, which is read by translation machinery as if it were guanosine. Aside from their role in generating protein diversity in the central nervous system, ADARs have been implicated in the hypermuta...

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Detalles Bibliográficos
Autores principales: Carpenter, Jennifer A, Keegan, Liam P, Wilfert, Lena, O'Connell, Mary A, Jiggins, Francis M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790459/
https://www.ncbi.nlm.nih.gov/pubmed/19941656
http://dx.doi.org/10.1186/1471-2156-10-75