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Hypothalamic Sirt1 Regulates Food Intake in a Rodent Model System

Sirt1 is an evolutionarily conserved NAD(+) dependent deacetylase involved in a wide range of processes including cellular differentiation, apoptosis, as well as metabolism, and aging. In this study, we investigated the role of hypothalamic Sirt1 in energy balance. Pharmacological inhibition or siRN...

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Detalles Bibliográficos
Autores principales: Çakir, Işin, Perello, Mario, Lansari, Omar, Messier, Norma J., Vaslet, Charles A., Nillni, Eduardo A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790615/
https://www.ncbi.nlm.nih.gov/pubmed/20020036
http://dx.doi.org/10.1371/journal.pone.0008322