Recruitment of Rad51 and Rad52 to Short Telomeres Triggers a Mec1-Mediated Hypersensitivity to Double-Stranded DNA Breaks in Senescent Budding Yeast

Telomere maintenance is required for chromosome stability, and telomeres are typically replicated by the action of telomerase. In both mammalian tumor and yeast cells that lack telomerase, telomeres are maintained by an alternative recombination mechanism. Here we demonstrated that the budding yeast...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Hsuan, Chang, Chia-Ching, Wong, Chui-Wei, Teng, Shu-Chun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790616/
https://www.ncbi.nlm.nih.gov/pubmed/20011546
http://dx.doi.org/10.1371/journal.pone.0008224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790616/
https://www.ncbi.nlm.nih.gov/pubmed/20011546
http://dx.doi.org/10.1371/journal.pone.0008224

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