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Mechanisms of ubiquitin transfer by the anaphase-promoting complex

The anaphase-promoting complex (APC) is a ubiquitin-protein ligase required for the completion of mitosis in all eukaryotes. Recent mechanistic studies reveal how this remarkable enzyme combines specificity in substrate binding with flexibility in ubiquitin transfer, thereby allowing the modificatio...

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Detalles Bibliográficos
Autores principales: Matyskiela, Mary E, Rodrigo-Brenni, Monica C, Morgan, David O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790831/
https://www.ncbi.nlm.nih.gov/pubmed/19874575
http://dx.doi.org/10.1186/jbiol184