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Generalized immune activation as a direct result of activated CD4(+ )T cell killing

BACKGROUND: In addition to progressive CD4(+ )T cell immune deficiency, HIV infection is characterized by generalized immune activation, thought to arise from increased microbial exposure resulting from diminishing immunity. RESULTS: Here we report that, in a virus-free mouse model, conditional abla...

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Detalles Bibliográficos
Autores principales: Marques, Rute, Williams, Adam, Eksmond, Urszula, Wullaert, Andy, Killeen, Nigel, Pasparakis, Manolis, Kioussis, Dimitris, Kassiotis, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790834/
https://www.ncbi.nlm.nih.gov/pubmed/19943952
http://dx.doi.org/10.1186/jbiol194