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The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells

INTRODUCTION: Previous studies indicate that overexpression of the membrane-associated mucin MUC4 is potently anti-adhesive to cultured tumor cells, and suppresses cellular apoptotic response to a variety of insults. Such observations raise the possibility that MUC4 expression could contribute to tu...

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Detalles Bibliográficos
Autores principales: Workman, Heather C, Miller, Jamie K, Ingalla, Ellen Q, Kaur, Rouminder P, Yamamoto, Diane I, Beckett, Laurel A, Young, Lawrence JT, Cardiff, Robert D, Borowsky, Alexander D, Carraway, Kermit L, Sweeney, Colleen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790847/
https://www.ncbi.nlm.nih.gov/pubmed/19761616
http://dx.doi.org/10.1186/bcr2364