Cargando…
The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells
INTRODUCTION: Previous studies indicate that overexpression of the membrane-associated mucin MUC4 is potently anti-adhesive to cultured tumor cells, and suppresses cellular apoptotic response to a variety of insults. Such observations raise the possibility that MUC4 expression could contribute to tu...
Autores principales: | Workman, Heather C, Miller, Jamie K, Ingalla, Ellen Q, Kaur, Rouminder P, Yamamoto, Diane I, Beckett, Laurel A, Young, Lawrence JT, Cardiff, Robert D, Borowsky, Alexander D, Carraway, Kermit L, Sweeney, Colleen |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790847/ https://www.ncbi.nlm.nih.gov/pubmed/19761616 http://dx.doi.org/10.1186/bcr2364 |
Ejemplares similares
-
Muc4\sialomucin Complex, A Specific Intramembrane Modulator of ERBB2/HER2/NEU, Potentiates Primary Tumor Growth and Suppresses Apoptosis in A Xenotransplanted Melanoma
por: Carraway, Coralie Carothers, et al.
Publicado: (2001) -
A New Monoclonal Antibody Demonstrates That Muc4, the Intramembrane Ligand for Erbb2/Her2/Neu, Is Overexpressed in Multiple Carcinomas
por: Zhang, Jin, et al.
Publicado: (2002) -
Membrane Mucin Muc4 Promotes Blood Cell Association with Tumor Cells and Mediates Efficient Metastasis in a Mouse Model of Breast Cancer
por: Rowson-Hodel, A.R., et al.
Publicado: (2017) -
Regulation of the T-box transcription factor Tbx3 by the tumour suppressor microRNA-206 in breast cancer
por: Amir, Sumaira, et al.
Publicado: (2016) -
Repurposing Cationic Amphiphilic Drugs and Derivatives to Engage Lysosomal Cell Death in Cancer Treatment
por: Hu, Michelle, et al.
Publicado: (2020)