Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1

DNA sequence motifs and epigenetic modifications contribute to specific binding by a transcription factor, but the extent to which each feature determines occupancy in vivo is poorly understood. We addressed this question in erythroid cells by identifying DNA segments occupied by GATA1 and measuring...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Wu, Weisheng, Cheng, Yong, King, David C., Harris, Robert S., Taylor, James, Chiaromonte, Francesca, Hardison, Ross C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790884/
https://www.ncbi.nlm.nih.gov/pubmed/19767611
http://dx.doi.org/10.1093/nar/gkp747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790884/
https://www.ncbi.nlm.nih.gov/pubmed/19767611
http://dx.doi.org/10.1093/nar/gkp747

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