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Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1
DNA sequence motifs and epigenetic modifications contribute to specific binding by a transcription factor, but the extent to which each feature determines occupancy in vivo is poorly understood. We addressed this question in erythroid cells by identifying DNA segments occupied by GATA1 and measuring...
Autores principales: | Zhang, Ying, Wu, Weisheng, Cheng, Yong, King, David C., Harris, Robert S., Taylor, James, Chiaromonte, Francesca, Hardison, Ross C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790884/ https://www.ncbi.nlm.nih.gov/pubmed/19767611 http://dx.doi.org/10.1093/nar/gkp747 |
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