An Alu-derived intronic splicing enhancer facilitates intronic processing and modulates aberrant splicing in ATM

We have previously reported a natural GTAA deletion within an intronic splicing processing element (ISPE) of the ataxia telangiectasia mutated (ATM) gene that disrupts a non-canonical U1 snRNP interaction and activates the excision of the upstream portion of the intron. The resulting pre-mRNA splici...

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Detalles Bibliográficos
Autores principales: Pastor, Tibor, Talotti, Gabriele, Lewandowska, Marzena Anna, Pagani, Franco
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790898/
https://www.ncbi.nlm.nih.gov/pubmed/19773425
http://dx.doi.org/10.1093/nar/gkp778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790898/
https://www.ncbi.nlm.nih.gov/pubmed/19773425
http://dx.doi.org/10.1093/nar/gkp778

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