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FSscan: a mechanism-based program to identify +1 ribosomal frameshift hotspots

In +1 programmed ribosomal frameshifting (PRF), ribosomes skip one nucleotide toward the 3′-end during translation. Most of the genes known to demonstrate +1 PRF have been discovered by chance or by searching homologous genes. Here, a bioinformatic framework called FSscan is developed to perform a s...

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Detalles Bibliográficos
Autores principales: Liao, Pei-Yu, Choi, Yong Seok, Lee, Kelvin H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790909/
https://www.ncbi.nlm.nih.gov/pubmed/19783813
http://dx.doi.org/10.1093/nar/gkp796