A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity

Paraoxonases (PONs) are a family of lactonases with promiscuous enzyme activity that has been implicated in multiple diseases. PON2 is intracellularly located, is the most ubiquitously expressed PON, and has the highest lactonase activity of the PON family members. Whereas some single-nucleotide pol...

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Detalles Bibliográficos
Autores principales: Stoltz, David A., Ozer, Egon A., Recker, Thomas J., Estin, Miriam, Yang, Xia, Shih, Diana M., Lusis, Aldons J., Zabner, Joseph
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Genomics, Proteomics, and Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790986/
https://www.ncbi.nlm.nih.gov/pubmed/19840942
http://dx.doi.org/10.1074/jbc.M109.051706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790986/
https://www.ncbi.nlm.nih.gov/pubmed/19840942
http://dx.doi.org/10.1074/jbc.M109.051706

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