Capturing Dopaminergic Modulation and Bimodal Membrane Behaviour of Striatal Medium Spiny Neurons in Accurate, Reduced Models

Loss of dopamine from the striatum can cause both profound motor deficits, as in Parkinson's disease, and disrupt learning. Yet the effect of dopamine on striatal neurons remains a complex and controversial topic, and is in need of a comprehensive framework. We extend a reduced model of the str...

Descripción completa

Detalles Bibliográficos
Autores principales: Humphries, Mark D., Lepora, Nathan, Wood, Ric, Gurney, Kevin
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791037/
https://www.ncbi.nlm.nih.gov/pubmed/20011223
http://dx.doi.org/10.3389/neuro.10.026.2009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791037/
https://www.ncbi.nlm.nih.gov/pubmed/20011223
http://dx.doi.org/10.3389/neuro.10.026.2009

Ejemplares similares