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Capturing Dopaminergic Modulation and Bimodal Membrane Behaviour of Striatal Medium Spiny Neurons in Accurate, Reduced Models
Loss of dopamine from the striatum can cause both profound motor deficits, as in Parkinson's disease, and disrupt learning. Yet the effect of dopamine on striatal neurons remains a complex and controversial topic, and is in need of a comprehensive framework. We extend a reduced model of the str...
Autores principales: | Humphries, Mark D., Lepora, Nathan, Wood, Ric, Gurney, Kevin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791037/ https://www.ncbi.nlm.nih.gov/pubmed/20011223 http://dx.doi.org/10.3389/neuro.10.026.2009 |
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