Progressive Purkinje Cell Degeneration in tambaleante Mutant Mice Is a Consequence of a Missense Mutation in HERC1 E3 Ubiquitin Ligase

The HERC gene family encodes proteins with two characteristic domains: HECT and RCC1-like. Proteins with HECT domains have been described to function as ubiquitin ligases, and those that contain RCC1-like domains have been reported to function as GTPases regulators. These two activities are essentia...

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Detalles Bibliográficos
Autores principales: Mashimo, Tomoji, Hadjebi, Ouadah, Amair-Pinedo, Fabiola, Tsurumi, Toshiko, Langa, Francina, Serikawa, Tadao, Sotelo, Constantino, Guénet, Jean-Louis, Rosa, Jose Luis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791161/
https://www.ncbi.nlm.nih.gov/pubmed/20041218
http://dx.doi.org/10.1371/journal.pgen.1000784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791161/
https://www.ncbi.nlm.nih.gov/pubmed/20041218
http://dx.doi.org/10.1371/journal.pgen.1000784

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