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Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

Since 2003, H5N1 influenza viruses have caused over 400 known cases of human infection with a mortality rate greater than 60%. Most of these cases resulted from direct contact with virus-contaminated poultry or poultry products. Although only limited human-to-human transmission has been reported to...

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Detalles Bibliográficos
Autores principales: Gao, Yuwei, Zhang, Ying, Shinya, Kyoko, Deng, Guohua, Jiang, Yongping, Li, Zejun, Guan, Yuntao, Tian, Guobin, Li, Yanbing, Shi, Jianzhong, Liu, Liling, Zeng, Xianying, Bu, Zhigao, Xia, Xianzhu, Kawaoka, Yoshihiro, Chen, Hualan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791199/
https://www.ncbi.nlm.nih.gov/pubmed/20041223
http://dx.doi.org/10.1371/journal.ppat.1000709